Risk factors for rapid axial length elongation with low concentration atropine for myopia control

Abstract Three hundred and twenty-eight myopic children, randomized to use either 0.01% (N = 166) or 0.02% 162) atropine were enrolled in this study. Gender, age, body mass index(BMI), parental myopia status, concentration used, pupil diameter, amplitude of accommodation, spherical equivalent refractive error (SER), anterior chamber depth (ACD) axial length (AL) collected at baseline 1 year after using atropine. Rapid AL elongation was defined as > 0.36 mm growth per year. Univariate analyses showed that children with rapid tend be younger, have a smaller BMI, atropine, narrow ACD, lower SER, shorter AL, change diameter between (all P < 0.05). Multivariate logistic regression confirmed associated younger ( 0.0001), (P 0.04), 0.03) 0.04). Younger baseline, less their treatment the two concentrations may undergo over 12 months control period.